Brugada syndrome with elevated cardiac biomarkers

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Cardiac autonomic dysfunction in Brugada syndrome.

BACKGROUND Patients with Brugada syndrome present with characteristic ECG abnormalities (atypical right bundle-branch block and ST-segment elevation) and life-threatening ventricular tachyarrhythmias despite structurally normal hearts. Involvement of the autonomic nervous system is suggested by the occurrence of ventricular tachyarrhythmias and sudden death at rest or during sleep and by change...

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Cardiac dynamics: modeling the Brugada syndrome

The Brugada syndrome is associated with an abnormal electrocardiogram (ECG), characterized by an elevation of the ST-segment. Since its discovery in 1992, it has gained increasing recognition, and today is believed to be responsible for 4% to 12% of all sudden deaths and around 20% of deaths in patients with structurally normal heart. Recently it has been discovered that it is caused by a mutat...

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Brugada syndrome—Malignant phenotype associated with acute cardiac inflammation?

Introduction Since the publication of the seminal case series in 1992 of right bundle branch block and persistent ST elevation in the right precordial leads associated with sudden death, there remain significant gaps in our knowledge surrounding Brugada syndrome. In particular, debate continues regarding its pathogenesis and has in part contributed to the difficulties in risk stratification of ...

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Risk factors for cardiac events in patients with Brugada syndrome

INTRODUCTION Inconsistent results have been reported about the risk stratification of patients with Brugada syndrome. We have summarized the evidence regarding the strength of association between 6 risk factors (family history of sudden cardiac death [SCD] or syncope, inducible ventricular arrhythmias on electrophysiology study [EPS], spontaneous type 1 Brugada electrocardiogram [ECG], male sex...

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Brugada syndrome.

Brugada syndrome is a rare cardiac arrhythmia characterized by electrocardiographic right bundle branch block and persistent ST-segment elevation in the right precordial leads. It is associated with ventricular fibrillation and a high risk for sudden cardiac death, predominantly in younger males with structurally normal hearts. Patients can remain asymptomatic, and electrocardiographic patterns...

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ژورنال

عنوان ژورنال: Case Reports

سال: 2013

ISSN: 1757-790X

DOI: 10.1136/bcr-2013-009918